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IMPORTANT SAFETY INFORMATION:

CSID vs. GSID

Is There Any Difference Between Congenital Sucrase-Isomaltase Deficiency and Genetic Sucrase-Isomaltase Deficiency?

The terms Congenital Sucrase-Isomaltase Deficiency (CSID) and Genetic Sucrase-Isomaltase Deficiency (GSID) are different names for the same condition.

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So why does one disease have two names?

This is largely due to how old someone is when they are diagnosed. The word congenital means present at birth, and most congenital disorders are diagnosed when one is an infant or in early childhood. However, many patients with Sucrose Intolerance due to CSID are being diagnosed later in life, when they are in their teens or even when they are adults. Since the term congenital is associated with an early childhood diagnosis, some consider it more accurate, when it is diagnosed in older patients, to call the disorder GSID rather than CSID. The word genetic implies that the disorder may have been diagnosed at any time – in infancy, childhood, teenage years, or in adulthood. However, either name refers to the same disorder, which has been present since birth.

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Important Safety Information for Sucraid® (sacrosidase) Oral Solution

  • Sucraid® may cause a serious allergic reaction. If you notice any swelling or have difficulty breathing, get emergency help right away.
  • Tell your doctor if you are allergic to, have ever had a reaction to, or have ever had difficulty taking yeast, yeast products, papain, or glycerin (glycerol).
  • Sucraid® does not break down some sugars that come from the digestion of starch. You may need to restrict the amount of starch in your diet. Your doctor will tell you if you should restrict starch in your diet.
  • Tell your doctor if you have diabetes, as your blood glucose levels may change if you begin taking Sucraid®. Your doctor will tell you if your diet or diabetes medicines need to be changed.
  • Some patients treated with Sucraid® may have worse abdominal pain, vomiting, nausea, or diarrhea. Constipation, difficulty sleeping, headache, nervousness, and dehydration have also occurred in patients treated with Sucraid®. Check with your doctor if you notice these or other side effects.
  • Sucraid® has not been tested to see if it works in patients with secondary (acquired) sucrase deficiency.
  • NEVER HEAT SUCRAID® OR PUT IT IN WARM OR HOT BEVERAGES OR INFANT FORMULA. Do not mix Sucraid® with fruit juice or take it with fruit juice. Take Sucraid® as prescribed by your doctor. Normally, half the dose of Sucraid® is taken before a meal or snack and the other half is taken during the meal or snack.
  • Sucraid® should be refrigerated at 36°F-46°F (2°C-8°C) and should be protected from heat and light.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.FDA.gov/medwatch or call 1-800-FDA-1088.

Indication

Sucraid® (sacrosidase) Oral Solution is an enzyme replacement therapy for the treatment of genetically determined sucrase deficiency, which is part of Congenital Sucrase-Isomaltase Deficiency (CSID).