Sucraid® (sacrosidase) Oral Solution is an enzyme replacement that facilitates breakdown of sucrose (sugar) into simpler forms for absorption from the intestine into the blood. It can help relieve the gastrointestinal symptoms associated with Genetic Sucrase-Isomaltase Deficiency/Congenital Sucrase-Isomaltase Deficiency, and as a result, patients can maintain a more normal diet with respect to sucrose-containing foods.
In 1960, Weijers and colleagues discovered Congenital Sucrase-Isomaltase Deficiency, an autosomal recessive disease of the small intestine that is also known as Genetic Sucrase-Isomaltase Deficiency. The disease was originally characterized by undetectable sucrase activity, a decrease of maltase activity to nearly one third of the normal level, and a varying degree of isomaltase activity.
Your doctor has prescribed Sucraid® either because you have been diagnosed with a deficiency of sucrase-isomaltase enzyme or because the doctor suspects you may have some deficiency of the enzyme and wishes to determine if Sucraid® would be of benefit.
Sucraid® does not break down starch (e.g., potato, bread, pasta) and some Genetic Sucrase-Isomaltase Deficiency patients also have an inability to absorb starch from their diet. Therefore, your doctor may recommend you restrict the amount of starch for two weeks after you first start Sucraid®, and gradually reintroduce starch to your diet. If symptoms return, you should consult your doctor. Keeping a dietary diary for the first few weeks of therapy is also recommended.